Diethylstilbestrol DES and Pregnancy Studies

Perhaps no drug has been more praised or more damned during the past 3 years than diethylstilbestrol (DES, stilbestrol) ~
1974 quote


  • how can, the exact same drug, be sold and used during the exact same decades (1960s and 1970s), for two fundamentally opposite goals : to prevent miscarriage AND as a contraceptive? Should it not be one or the other?
  • And how can a drug be considered safe, when there are warnings about its toxicity?
  • And how can a drug be officially (re)approved for usage when its carcinogenic effects are known and proven?

New Generations (People exposed in-Utero)

Pregnancy Outcome in DES Offspring
and Implications for Childbearing

Direct Usage and Exposure

DES used as an Emergency Contraception

DES (very wrongly) used to  “Prevent Pregnancy Complications

(Early) Warnings about DES Toxicity

For different topics, please see Diethylstilbestrol DES Studies.