Reproductive problems in the DES-exposed female

image of pregnancy
Reproductive problems in the DES-exposed female, 1980 findings. Pregnant-25-weeks.


Obstetrics and gynecology, NCBI PubMed, PMID:7366902, 1980 Apr.

The records of 25 diethylstilbestrol-exposed women under treatment for reproductive dysfunction were reviewed.

A tendency toward:

  • pregnancy wastage (5 of 10 patients),
  • ectopic pregnancy (2 of 8 patients),
  • cervical factor infertility (15 of 20 patients),
  • hysterographic abnormalities (15 of 19 patients),
  • and ovulatory dysfunction (10 of 25 patients) was noted.

With the exceptions of ovulation induction and cervical cerclage, no means of treatment can be recommended.

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