In utero exposure to DES results in a variety of harmful effects, including long-term harms.
Mental health issues reported for DES daughters and DES sons include depression, bipolar disorder, behavioural disorders and schizophrenia.
Sources studies about DES and mental health, psychological issues, psychiatric disorders and sexual orientation :
- 2019 Chemical castration with DES as an alternative to prison.
- 2019 Prenatal Diethylstilbestrol Exposure and Risk of Depression in Women and Men.
- 2018 Association of Exposure to Diethylstilbestrol During Pregnancy With Multigenerational Neurodevelopmental Deficits.
- 2018 Evidence for Link Between Mental Disorders and in Utero Exposure to Synthetic Hormones: A Long and Crucial History.
- 2018 Neurodevelopmental disorders in children exposed in utero to synthetic progestins: analysis from the national cohort of the Hhorages Association.
- 2017 Impact of prenatal exposure to diethylstilbestrol (DES) on psychological outcome: a national survey of DES daughters and unexposed controls.
- 2017 Methylomic changes in individuals with psychosis, prenatally exposed to endocrine disrupting compounds: Lessons from diethylstilbestrol.
- 2016 Association between fetal DES-exposure and psychiatric disorders in adolescence/adulthood : evidence from a French cohort of 1002 prenatally exposed children.
- 2016 Endocrine disruptors and psychiatric disorders in children exposed in utero: evidence from a French cohort of 1002 prenatally exposed children and the example of diethylstilbestrol (DES) as a model for PE study.
- 2016 Environmental signaling: from environmental estrogens to endocrine-disrupting chemicals and beyond.
- 2016 Methylomic Changes in Individuals with Psychosis and Prenatally Exposed to Diethylstilbestrol.
- 2015 Distilbène et troubles psychiatriques?
- 2015 Effects of diethylstilbestrol exposure during gestation on both maternal and offspring behavior.
- 2015 Prenatal exposure to endocrine disruptors and neurodevelopment risk : study of siblings exposed to diethylstilbestrol.
- 2014 Epigenetics of schizophrenia : a review.
- 2012 Behavioral and Somatic Disorders in Children Exposed in Utero to Synthetic Hormones: A Testimony-Case Study in a French Family Troop.
- 2012 Diethylstilbestrol and risk of psychiatric disorders: a critical review and new insights.
- 2012 Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems.
- 2011 Distilbène, effets psychiatriques – Rapport Hhorages 2011.
- 2011 Endocrine disrupters and effects on behavioral disorders: No, we have not as yet learnt all our lessons concerning the DES story.
- 2011 Endocrine disruptors and behavioural anomalies.
- 2011 Prenatal endocrine influences on sexual orientation and on sexually differentiated childhood behavior.
- 2011 Psychological consequences of DES exposure in utero.
- 2010 Diethylstilbestrol Exposure in Utero and Depression in Women.
- 2010 Epigenetics, brain, behavior, and the environment.
- 2009 Hypermethylation of Homeobox A10 by in Utero Diethylstilbestrol Exposure: An Epigenetic Mechanism for Altered Developmental Programming.
- 2008 Entre mère et fille, le DES, aspects psychologiques.
- 2007 Effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits.
- 2007 Serious psychiatric outcome of subjects prenatally exposed to diethylstilboestrol in the E3N cohort study.
- 2005 Early exposure to a low dose of bisphenol A affects socio-sexual behavior of juvenile female rats.
- 2004 Endocrine disrupters as disrupters of brain function: a neurosteroid viewpoint.
- 2004 Low-dose perinatal diethylstilbestrol exposure affected behaviors and hypothalamic estrogen receptor-alpha-positive cells in the mouse.
- 2004 Obstetrical complications and subsequent schizophrenia in adolescent and young adult offsprings: is there a relationship?
- 2004 Perinatal risk factors for schizophrenia: how specific are they?
- 2003 Castration of Sex Offenders: Prisoners’ Rights Versus Public Safety.
- 2003 Psychosexual characteristics of men and women exposed prenatally to diethylstilbestrol.
- 2002 Long-term psychiatric and behavioural consequences of prenatal exposure to psychoactive drugs.
- 2000 A focus group study of DES daughters: implications for health care providers.
- 2000 Does prenatal exposure to diethylstilbestrol (DES) have psychiatric consequences?
- 2000 Language lateralization and handedness in women prenatally exposed to diethylstilbestrol (DES).
- 1999 Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control study.
- 1999 Prenatal exposure to endocrine disrupting chemicals: effects on behavioral development.
- 1999 Schizophrenic patients and their first-degree relatives show an excess of mixed-handedness.
- 1998 Cognitive ability and cerebral lateralisation in transsexuals.
- 1998 Environmental endocrine modulators and human health: an assessment of the biological evidence.
- 1997 Obstetric complications and age at onset in schizophrenia: an international collaborative meta-analysis of individual patient data.
- 1996 Cerebral lateralization is delayed in children who later develop schizophrenia.
- 1996 Prenatal exposure to diethylstilbestrol and the mother-daughter relationship.
- 1996 The effects of diethylstilbestrol (DES) before birth on the development of masculine behavior in juvenile female rhesus monkeys.
- 1995 Diethylstilbestrol (DES)-Related Endocrine Disturbances in Women : A Story with No End, Yet
- 1995 Handedness and other laterality indices in women prenatally exposed to DES.
- 1995 Prenatal estrogens and the development of homosexual orientation.
- 1994 Androgen and the development of human sex-typical behavior: rough-and-tumble play and sex of preferred playmates in children with congenital adrenal hyperplasia (CAH).
- 1994 Handedness in women with intrauterine exposure to diethylstilbestrol.
- 1993 Psychopathology and social functioning in men prenatally exposed to diethylstilbestrol (DES).
- 1992 Effects of prenatal exposure to diethylstilbestrol (DES) on hemispheric laterality and spatial ability in human males.
- 1992 Prenatal exposure to diethylstilbestrol (DES): childhood play behavior and adult gender-role behavior in women.
- 1991 Increased risk of profound weight loss among women exposed to diethylstilbestrol in utero.
- 1989 The development of gender-related behavior in females following prenatal exposure to diethylstilbestrol (DES).
- 1988 Physical and psychological problems associated with exposure to diethylstilbestrol (DES).
- 1988 The psychological impact of prenatal DES exposure in women: a comparison of short-term and long-term effects.
- 1987 Depression and diethylstilbestrol exposure in women.
- 1987 Obstetric complications, neurodevelopmental deviance, and risk of schizophrenia.
- 1987 Psychopathology in prenatally DES-exposed females: current and lifetime adjustment.
- 1987 Psychosis and prenatal exposure to diethylstilbestrol.
- 1986 Long-Term Distress Subsequent to Pregnancy Drug Administration: Women with in Utero Diethylstilbestrol (DES) Exposed Daughters.
- 1986 Prenatal Diethylstilbestrol Exposure : Behavioral Consequences in Humans.
- 1985 Cerebral lateralization. Biological mechanisms, associations, and pathology.
- 1985 Estrogens before birth and development of sex-related reproductive traits in the female guinea pig.
- 1985 Sexual activity level and sexual functioning in women prenatally exposed to diethylstilbestrol.
- 1985 Sexual orientation after prenatal exposure to exogenous estrogen.
- 1985 Vulnerability to stress among women with in utero diethylstilbestrol (DES) exposed daughters.
- 1984 Pre- and postnatal influence of testosterone propionate and diethylstilbestrol on differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats.
- 1984 Prenatal exposure to diethylstilbestrol (DES) and the development of sexually dimorphic cognitive abilities and cerebral lateralization.
- 1984 Psychosexual milestones in women prenatally exposed to diethylstilbestrol.
- 1984 Screening and Management of Diethylstilbestrol Exposed Offspring – Psychological Support.
- 1983 A randomized double-blind controlled trial of the value of stilboestrol therapy in pregnancy: long-term follow-up of mothers and their offspring.
- 1983 Diethylstilbestrol Revisited: A Review of the Long-Term Health Effects.
- 1980 Observations on the psychological impact of diethylstilbestrol exposure and suggestions on management.
- 1980 Prenatal ‘female hormone’ administration and psychosexual development in human males.
- 1979 Emotional distress in morning-after pill patients.
- 1978 Abnormal gonadotropin secretory responses to LRH in transsexual women after diethylstilbestrol priming.
- 1977 Prenatal exposure to synthetic progestins and estrogens: Effects on human development.
- 1977 Psychological effects of diethylstilbestrol exposure.
- 1973 Prenatal Exposure to Female Hormones : Effect on Psychosexual Development in Boys.
- 1959 The Clinical use of Stilboestrol for Suppression of Sexual Behaviour of Chronically Ill Male Psychiatric Patients.
For different topics, please see Diethylstilbestrol DES Studies.