DES used as an emergency contraception, Czechoslovakia, 1977
55 women were administered a series of postcoital contraceptives, 35 of whom received only a single application and 20 received the preparations for more than 1 cycle (more than 2 but less than 13).
34 women of the 1st group (48 hours after unprotected coitus) and 7 women from the 2nd group were administered diethylstilbestrol (DES) for 5 days for a total of 250 mg.
The remaining subjects were given norethisterone Spofa for 3 days at 30 mg/day.
Results from this administration in the sense of a general contraceptive were not considered favorable, primarily due to contraindications in regard to physiological side effects, particularly with DES. DES proved to be the most successful in preventing pregnancy.
- Postcoital contraceptives in clinical practice, NCBI PubMed, PMID: 321139, 1977 Feb.
- Image credit proclinical.