Published: 01 April 1940 (that’s right, on April fools day).
Summary
Diethylstilbestrol when administered to women possessed the same physiological properties as do the hormonal estrogens. The therapeutic use of diethylstilbestrol is greatly limited because of the persistent nausea and occasional vomiting that was induced in more than one’half of the patients.
Sources
- THE ACTION OF DIETHYLSTILBESTROL IN GYNECOLOGICAL DYSFUNCTIONS, academic doi.org/10.1210/endo-26-4-581, 01 April 1940.
- Free full text available via sci-hub.
DES DIETHYLSTILBESTROL RESOURCES
- Source DES and pregnancy studies.
- Diethylstilbestrol DES studies by topics.