Hysteroscopic metroplasty in DES-exposed and hypoplastic uterus

image of Septate-uterus
Septate uterus: partial (1 and 2), complete (3), complete with septate cervix (4), and complete with cervical and vaginal septation (5). JMIG.

Abstract

Hysteroscopic metroplasty for uterine enlargement: a treatment for diethylbestrol-exposed and hypoplastic uteri, Journal de gynécologie, obstétrique et biologie de la reproduction, NCBI PubMed PMID: 8901300, 1996. Full text: Hysteroscopic metroplasty in diethylbestrol-exposed and hypoplastic uterus: a report on 24 cases , Human reproduction (1998) 13 (10): 2751-2755, oxfordjournals, 1996.

OBJECTIVE
To determine the feasibility of correcting the uterine deformity in the diethylbestrol-exposed uterus and hypoplastic uterus.

DESIGN
Hysteroscopic metroplasty. Patients served as their own controls.

PATIENTS
Five patients referred for primary sterility (2 cases) or primo-secondary infertility with recurrent pregnancy loss or ectopic pregnancy (3 cases). Three of them had been exposed in utero to diethylbestrol. All of them have a hypoplastic uterus or uterine deformities as seen by hysterosalpingogram.

OUTCOME MEASURES
Postoperative hysterosalpingogram aspect. Ability to conceive and carry pregnancy to livebirth.

RESULTS
All the postoperative hysterosalpingograms appeared more normal than the preoperatively. Three patients have conceived since surgery.

CONCLUSION
Hysteroscopic metroplasty is feasible. It gives good anatomic results. This technique could be used in the patients with diethylbestrol-exposed or hypoplastic uteri, with severe infertility, recurrent pregnancy loss or implantations failures in a IVF program.

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