IPPF medical bulletin, 1967
Estrogens have been used as postcoital contraceptives with success.
Of 100 women who had midcycle coitus and were given stilbesterol or ethynyl estradiol for 4 or more days, none became pregnant.
Estrogen administration lowered basal body temperature, and endometrial biopsies showed retarded endometrium.
Nausea was present among 40% of the women and 12% experienced breast soreness.
The hypothesised mechanisms of action include: accelerated ovum transport, change in stickiness of the blastocyte, and changes in the implantation site, all leading to the prevention of implantation.
- Postcoital contraception, IPPF medical bulletin, NCBI PubMed PMID: 12254703, 1967.
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