Premenopausal breast cancer after in-utero exposure to stilboestrol

Breast cancer cases reported in premenopausal DES Daughters

1996 Study Abstract

Two premenopausal women recently presented to the British Columbia Cancer Agency with a history of intrauterine exposure to stilboestrol (diethylstilboestrol, DES) and newly diagnosed breast cancer.

  1. The first, age 28, had known DES sequelae with a bicornate uterus and presented with stage IV breast cancer.
  2. The second, age 34, presented with stage II breast cancer and no previous health problems.

Neither patient had any known familial history of breast cancer, or any other risk factors.

Sources

DES DIETHYLSTILBESTROL RESOURCES

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