DES “treatment” of a gender-dysphoric transvestite

DES usage as a “gender management”

1985 Study Abstract

A synthetic ovarian hormone, diethylstilbestrol, was used to reduce the desire to cross-dress in a 65-year-old, gender-dysphoric transvestite.

Antiandrogens may be of use in treating patients refractory or inaccessible to other clinical approaches.


  • Antiandrogenic treatment of a gender-dysphoric transvestite, Journal of sex & marital therapy, NCBI PubMed PMID: 3159907, 1985 Summer.
  • Image credit Serhii Borodin.

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