American Society for Reproductive Medicine, Fertility and Sterility, 1999
To review the effects of in utero exposure to diethylstilbestrol (DES) on müllerian development and subsequent reproductive function.
The literature on DES and reproductive function was reviewed and summary data are presented. The studies were identified through the computerized MEDLINE database and a manual search of relevent bibliographies.
In utero exposure to DES resulted in reduced fertility and increased rates of ectopic pregnancy, spontaneous abortion, and preterm delivery.
An understanding of the reproductive performance of women who were exposed to DES in utero is useful for counseling these patients regarding their risks and treatment options.
- Effect of diethylstilbestrol on reproductive function, Fertility and Sterility, Volume 72, Issue 1, Pages 1–7, July 1999.
- Featured image credit Ricardo Gomez Angel.