Long-term follow-up of DES Mothers

Long-term follow-up of mothers who received high doses of stilboestrol and ethisterone in pregnancy

1980 Study Abstract

The report by Dr Valerie Beral and Linda Colwell linking oestrogen therapy during pregnancy with later appearance (after 18-22 years) of breast cancer prompted us to review studies on oral contraceptives. …

… The data in the table indicate an increased risk of breast cancer among women with a positive history of oral contraceptive use but only after they have passed into their fifth or sixth decade. Breast cancer is common in women in their later years; a small increase in risk would therefore mean a large increase in the absolute number of cases. Most oral contraceptive users have not yet reached the critical age. Future studies should address this potential problem.

Sources

  • Full text (free access) : Long-term follow-up of mothers who received high doses of stilboestrol and ethisterone in pregnancy, British medical journal, NCBI PubMed PMC1715108, 1980 Dec.
  • Featured image pexels.
DES DIETHYLSTILBESTROL RESOURCES

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