DES Effect on Males, Pediatrics, January 1978, VOLUME 61 / ISSUE 1 61/1/154.3.
We have found defects in the urogenital tract of males exposed to diethylstilbestrol (DES) in utero, but the anomalies are different than those expected from the data of Henderson and co-workers. They reported an increased incidence of suspected urethral stenosis in boys exposed to DES. Their conclusion was drawn from the response of 225 DES-exposed males to a questionnaire.
We have thoroughly examined 163 DES-exposed males and found a significantly increased incidence of
- hypotrophic testes,
- low ejaculate volumes,
- epididymal cysts,
- and microphallus.